W81XWH21P0021
Purchase Order
Overview
Government Description
MEDICAL RESEARCH AND DEVELOPMENT DHA SBIR PH I H202-002-0014
Awardee
Awarding Agency
Place of Performance
College Station, TX United States
Pricing
Fixed Price
Set Aside
Small Business Set Aside - Total (SBA)
Extent Competed
Full And Open Competition After Exclusion Of Sources
Related Opportunity
HQ003420R2000
Analysis Notes
Amendment Since initial award the Potential End Date has been extended from 08/11/21 to 10/11/21.
Lynntech was awarded
Purchase Order W81XWH21P0021 (W81XWH-21-P-0021)
for Medical Research And Development Dha Sbir Ph I H202-002-0014
worth up to $249,997
by Army Medical Research and Development Command
in January 2021.
The contract
has a duration of 9 months and
was awarded
through SBIR Topic A Multiplexed, Functional Assay to Determine the Bactericidal Activity of Antibodies Against Multiple Enteric Bacterial Pathogens
with a Small Business Total set aside
with
NAICS 541715 and
PSC AN11
via direct negotiation acquisition procedures with 41 bids received.
SBIR Details
Research Type
Small Business Innovation Research Program (SBIR) Phase I
Title
Multiplexed, high-throughput functional assay to evaluate bactericidal activity of antibodies against Shigella
Related Solicitation
Abstract
Shigella infection is one of most common medical problems for deployed military personnel. Shigella infection causes acute diarrheal as well as chronic functional bowel disorders and reactive arthritis, and the infection keeps our service members out of fight, threatening unit readiness. Therefore, the need of prevention of Shigella infection has become a high priority for US Service Members. A safe and effective Shigella vaccine is therefore of paramount importance. Monitoring of Shigella vaccine effectiveness could be expedited and simplified by the ability to evaluate antibody activities. The bactericidal activity of Shigella antibodies has been used as a measure to evaluate the functional activity of antibodies. However, conventional bactericidal activity assay is based on counting the surviving bacterial forming units on plates through overnight culture, which is labor-sensitive, time-consuming, and not suitable for large-scale studies. To test the antibody against multiple serotypes, the assay must be performed on each serotype and large qualities of samples are needed. A multiplexed, high-throughput antibody bactericidal assay against an array of Shigella strains would enable large-scale sample analysis and support rapid vaccine development. Lynntech proposes to develop a rapid, high-throughput, and cost-effective multiplex assay capable of simultaneously evaluating bactericidal activity of antibodies against multiple Shigella serotypes. This assay is being designed to be simple and has the capability to provide sample-to-answer results in four hours. Furthermore, Lynntech's bactericidal assay can serve as a multiplex detection and qualification platform to evaluate bactericidal activity of antibodies without the need for culture.
Research Objective
The goal of phase I is to establish the technical merit, feasibility, and commercial potential of proposed R&D efforts and determine the quality of performance of the small business awardee organization.
Topic Code
DHA202-002
Agency Tracking Number
H202-002-0014
Solicitation Number
20.2
Contact
Dakota Burleson
Status
(Complete)
Last Modified 7/6/21
Period of Performance
1/12/21
Start Date
10/11/21
Current End Date
10/11/21
Potential End Date
Obligations
$250.0K
Total Obligated
$250.0K
Current Award
$250.0K
Potential Award
Award Hierarchy
Purchase Order
W81XWH21P0021
Subcontracts
Activity Timeline
Transaction History
Modifications to W81XWH21P0021
People
Suggested agency contacts for W81XWH21P0021
Competition
Number of Bidders
41
Solicitation Procedures
Negotiated Proposal/Quote
Evaluated Preference
None
Commercial Item Acquisition
Commercial Item Procedures Not Used
Simplified Procedures for Commercial Items
No
Other Categorizations
Subcontracting Plan
Plan Not Required
Cost Accounting Standards
Exempt
Business Size Determination
Small Business
Defense Program
None
DoD Claimant Code
Services
IT Commercial Item Category
Not Applicable
Awardee UEI
PMVAL8J63516
Awardee CAGE
0LHF9
Agency Detail
Awarding Office
W81XWH W4PZ USA MED RSCH ACQUIS ACT
Funding Office
W23RYX
Created By
teely.e.shaffer.civ@mail.mil
Last Modified By
teely.e.shaffer.civ@mail.mil
Approved By
teely.e.shaffer.civ@mail.mil
Legislative
Legislative Mandates
None Applicable
Performance District
TX-17
Senators
John Cornyn
Ted Cruz
Ted Cruz
Representative
Pete Sessions
Modified: 7/6/21