75N91023C00053
Definitive Contract
Overview
Government Description
ARPA-H SBIR PHASE II TOPIC 4 FOR INTRA-OPERATIVE CONTRAST AGENTS
Awardee
Awarding / Funding Agency
Place of Performance
Columbia, MD 21046 United States
Pricing
Fixed Price
Set Aside
Small Business Set Aside - Total (SBA)
Extent Competed
Full And Open Competition After Exclusion Of Sources
Optosurgical was awarded
Definitive Contract 75N91023C00053 (75N910-23-C-00053)
for Arpa-H Sbir Phase Ii Topic 4 For Intra-Operative Contrast Agents
worth up to $3,500,000
by the National Institutes of Health
in September 2023.
The contract
has a duration of 2 years and
was awarded
through solicitation A Solicitation of the Advanced Research Project Agency for Health (ARPA-H) for Small Business Innovative Research (SBIR) Contract Proposals- SOLICITATION AND ALL AMENDMENTS (1-4)
with a Small Business Total set aside
with
NAICS 541715 and
PSC AN13
via direct negotiation acquisition procedures with 2 bids received.
SBIR Details
Research Type
Small Business Innovation Research Program (SBIR) Phase II
Title
ARPA-H SBIR PHASE II TOPIC 4 FOR INTRA-OPERATIVE CONTRAST AGENTS
Abstract
The project aims to advance the development of BL-760, a near-infrared contrast agent designed for clear intraoperative identification of bile ducts. This novel dye addresses the significant medical issue of bile duct injury during hepatobiliary surgeries (e.g., cholecystectomy, hepatectomy), impacting over 1 million patients annually. The project plans to produce BL-760 with high quality standards (GMP) and to conduct rigorous safety tests in a controlled lab environment (GLP), at the allow for Investigational New Drug (IND)-enabling studies to test the dye in humans. The project outcome will improve patient outcomes and set a new standard of care in the field of hepatobiliary surgery.
Research Objective
The goal of phase II is to continue the R&D efforts initiated in Phase I. Funding is based on the results achieved in Phase I and the scientific and technical merit and commercial potential of the project proposed in Phase II.
Topic Code
AH04
Agency Tracking Number
75N91023C00053
Solicitation Number
75N91023R00041
Contact
Yoseph Kim
Status
(Open)
Last Modified 4/30/25
Period of Performance
9/15/23
Start Date
9/14/25
Current End Date
9/14/25
Potential End Date
Obligations
$3.5M
Total Obligated
$3.5M
Current Award
$3.5M
Potential Award
Award Hierarchy
Definitive Contract
75N91023C00053
Subcontracts
Activity Timeline
Labor Services Billing
Annual labor billing rates and FTE reported for 75N91023C00053
| Year | Services Invoiced | Hours | FTE | Blended Rate |
|---|---|---|---|---|
| 2023 | $5,900 | 100.0 | 0.1 | $59.00 |
Opportunity Lifecycle
Procurement history for 75N91023C00053
Transaction History
Modifications to 75N91023C00053
People
Suggested agency contacts for 75N91023C00053
Competition
Number of Bidders
2
Solicitation Procedures
Negotiated Proposal/Quote
Evaluated Preference
None
Commercial Item Acquisition
Commercial Item Procedures Not Used
Simplified Procedures for Commercial Items
No
Other Categorizations
Subcontracting Plan
Plan Not Required
Cost Accounting Standards
Exempt
Business Size Determination
Small Business
Awardee UEI
N5FFBMLQHAJ9
Awardee CAGE
8BQW2
Agency Detail
Awarding Office
75N992 ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Funding Office
75N992
Created By
hhsamay
Last Modified By
hhsamay
Approved By
hhsamay
Legislative
Legislative Mandates
None Applicable
Performance District
MD-03
Senators
Benjamin Cardin
Chris Van Hollen
Chris Van Hollen
Representative
John Sarbanes
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| Advanced Research Projects Agency for Health-NIH, National Institutes of Health, Department of Health and Human Services (075-0837) | Health research and training | Other services from non-Federal sources (25.2) | $3,500,000 | 100% |
Modified: 4/30/25