Transmission Electron Microscope

Background
The Department of Health and Human Services (DHHS), National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) requires the procurement of a next generation screening electron microscope.

This contract aims to enhance research capabilities by providing advanced imaging technology for negative-stain grids screening.

Work Details
The contractor is responsible for supplying a 120 kV Transmission Electron Microscope with specific features including:
- A Windows 11-based GUI for displaying microscope conditions and user logon with lock-out mechanisms.
- Operation from 20 kV to 120 kV with automatic alignment recall at key voltages.
- Parfocal design ensuring focus remains unchanged across magnifications, with minimal image rotation.
- Complete dry-pumping system using Turbo Molecular Pump and diaphragm pump, with vacuum monitoring gauges.
- Standard inclusion of motorized aperture control, beam stop, and software-based control for various parameters.
- Integration of a 2k x 2k scientific CMOS camera into the control software, allowing for high-performance imaging.
- Features to prevent vacuum leaks, maintain constant brightness during magnification changes, and allow specimen exchange without shutting off the beam.
- An anti-contaminator device integrated into the objective lens pole piece to protect cryo-EM specimens from ice contamination.
- Goniometer supporting tilts up to ±80º for tomography applications, with options for multiple specimen holders.
- Seamless mode selection between LOWMAG, MAG, and SADIFF without requiring realignment.
- Software capabilities for montaging grids and supporting various microscopy workflows including tomography and Single Particle Analysis (SPA).
- A comprehensive warranty covering unlimited visits and parts after installation.

Period of Performance
Delivery within 6 months after receipt of order; warranty begins upon installation in the customer’s lab.

Place of Performance
Bethesda MD 20892 UNITED STATES

Bidder Requirements
Bidders must provide a detailed proposal that meets all specified technical requirements outlined in the solicitation. No specific security clearances or certifications are mentioned; however, bidders should demonstrate experience in delivering advanced microscopy equipment.