Surface Plasmon Resonance (SPR) Instrument- Brand Name or Equal   2

Introduction
This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

Project Summary
The National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Research Center (VRC) of the Structural Biology Section is seeking a Surface Plasmon Resonance (SPR) Instrument to obtain biophysical and structural data for macromolecules.
Specifically, NIAID, VRC is seeking a Surface Plasmon Resonance (SPR) Instrument that can perform the following applications:
Need for one (1) High-throughput Surface Plasmon Resonance Instrument. This instrument should include the following:
1. Instrument and on-instrument Analysis Software license) with PC and Monitor.
2. A One Year Warranty should be included.
3. A Custom Wheeled Bench which will allow for 360-degree walk-around access to the instrument for servicing.
4. Analysis Software (one off-instrument license)
5. Reagent Starter Kit
6. Installation
7. Training at the installation location.

The SPR system must also include all the requirements listed below.
1. The physical dimensions should not exceed 58 in x 33 in x 35 in (147.3 cm x 83.8 cm x 88.9 cm).
2. The maximum weight of the instrument should not exceed 740 lbs.
3. The analysis temperature range should be within 15 40 C.
4. The sample storage should be temperature controlled with a range of 10 25 C.
5. The instrument should be capable of high-throughput sample capture with 96 parallel prints and up to 384 spots.
6. A single flow cell that should cover the entire 384 spots.
7. The baseline noise should be < 0.8 RU RMS Single Channel Mode, 98% of ROIs).
8. The baseline drift should be < 0.17 RU/min.
9. The data collection rate should be at 1.2 Hz
10. The maximum association rate (Ka) measured should be up to 107 M-1 s-1
11. The dissociation rate range should be 10-5 to 0.5 s-1
12. The sample requirement for multi-channel should be < 220 uL and must be recoverable.
13. The sample requirement for single-channel should be < 300 uL.
14. The flow rate for multi-channel should be < 50 ul/min
15. The flow rate for single-channel should be > 1.5 ml/min
16. The injection flow should be bi-directional
17. The sample deck should hold at least 3 96-well plates or 384-well plates.

Anticipated Period of Performance
It is anticipated that an award will be made on or about September 09, 2024. Delivery of equipment will be required as soon as possible.

Capability Statement/Information Sought
If your organization has the potential capacity to provide a Surface Plasmon Resonance (SPR) Instrument which meets the minimum salient characteristics listed above, please provide the following information:
1. Organization name, address, point of contact, email address, website address, telephone number, UEI number
2. Type of business (e.g., 8(a), HUBZone, Other than Small, etc.) pursuant to the applicable NAICS code
3. Identification of any Best-in-Class contract vehicles including Government Wide Acquisition Contracts (GWAC) (e.g., GSA schedule, NITAAC) they may possess or are aware of that would support this possible requirement. If your organization does not provide the products/services under a GWAC, please identify availability as OPEN MARKET ONLY.
4. Tailored capability statement addressing the capability of the instrument to meet NIAID's minimum salient characteristics. Capability document shall be no more than six pages.
5. Place of manufacture for the Surface Plasmon Resonance (SPR) Instrument and if applicable, any accessories/components.
6. Evidence that the organization is an authorized reseller or manufacturer of the instrument. Only Original Equipment Manufacturer (OEM) products are acceptable.

Submission Instructions
Interested businesses who consider themselves qualified to provide the above listed Surface Plasmon Resonance (SPR) Instrument are invited to submit a response to this Sources Sought Notice by July 15, 2024, at 3:00 PM EST. All responses under this Sources Sought Notice shall be emailed to Hershea Vance at hershea.vance@nih.gov.

Disclamer and Important Notes
This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality
No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).