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SOURCES SOUGHT: Mass Spectrometry Reagents

ID: 75N95025Q00118 • Type: Sources Sought

Description

This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations.

The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition.

Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.

Background: The National Institute on Aging (NIA) requires the acquisition of Mass Spectrometry Reagents for mass spectrometry-based proteomics, peptidomics, lipidomics and metabolomics to understand the underlying biology of Alzheimer's Disease and Related Dementias.

Purpose and Objectives: The NIA's objective is to create a national resource of isogenic sets of Alzheimer's Disease and Related Dementias mutation iPSC lines, complimented by foundational phenotypic datasets from differentiated disease-relevant cells derived from these lines. The NIA anticipates that this resource will substantially accelerate the pace of mechanistic discovery regarding how Alzheimer's Disease and Related Dementia mutations cause disease.

Project requirements: Please see the PURCHASE DESCRIPTION attached to this posting.

Anticipated delivery dates:

Base Quantity: July 7, 2025

Optional 1 Quantity: July 7, 2026

Optional 2 Quantity: July 7, 2027

Capability statement /information sought.

Small business concerns that believe they possess the capabilities to provide the required services should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Small businesses must also provide their Company Name, Unique Entity ID number from SAM.gov, Physical Address, and Point of Contact Information.
Interested small businesses are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

The respondent must also provide their Unique Entity ID number from SAM.gov, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements.

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2 x 11 paper size, with 1 top, bottom, left and right margins, and with single or double spacing.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.

The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested.

The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted.

The response must be submitted to Rashiid Cummins, Contract Specialist, at e-mail address Rashiid.Cummins@nih.gov

The response must be received on or before January 21st, 2025, 3:00 PM, Eastern Time.

Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).

Background
The National Institute on Aging (NIA) requires the acquisition of Mass Spectrometry Reagents for mass spectrometry-based proteomics, peptidomics, lipidomics, and metabolomics to understand the underlying biology of Alzheimer’s Disease and Related Dementias.

The NIA’s objective is to create a national resource of isogenic sets of Alzheimer’s Disease and Related Dementias mutation iPSC lines, complemented by foundational phenotypic datasets from differentiated disease-relevant cells derived from these lines. This resource is anticipated to substantially accelerate the pace of mechanistic discovery regarding how Alzheimer’s Disease and Related Dementia mutations cause disease.

Work Details
The contract involves the delivery of specific Mass Spectrometry Reagents as follows:
1. ThermoFisher EASY-SPRAY HPLC Column PART# ES903 (QTY=90)
2. ThermoFisher Acclaim PepMap HPLC Column PART# 164535 (QTY=150)
3. ThermoFisher CAP SNP 11MM BL PE S/T 100/PK PART# 6ARC11ST1 (QTY=60)
4. ThermoFisher VIAL 0.3ML CLR PP SNP CON INS 100/PK PART# 6ERV11-03PPC (QTY=60)

Salient characteristics include:
- All deliverables must be packaged, marked, and shipped according to Government specifications.
- Deliverables must be marked with the contract number and Contractor name.
- The Contractor guarantees that all required materials will be delivered in immediately usable and acceptable condition.

Specifications for key products:
- **ThermoFisher EASY-SPRAY HPLC Column**:
- Column Format: Analytical Column, EASY-Spray
- Diameter: 75 μm
- Length: 500 mm
- Max Pressure: 14500 psi (1000 bar)
- Particle Size: 2 μm
- pH: 2 to 8
- Pore Size: 100 Å
- Surface Area: 450 m²/g
- Temperature: 60°C
- USP Type: L1
- Stationary Phase: C18
- **ThermoFisher Acclaim PepMap HPLC Column**:
- Column Format: Trap Column, NanoViper
- Diameter: 0.075 mm
- Length: 150 mm
- Max Pressure: 7250 psi (500 bar)
- Particle Size: 3 μm
- pH: 2 to 8
- Pore Size: 100 Å

Period of Performance
Base Quantity delivery by July 7, 2025; Optional deliveries by July 7, 2026 and July 7, 2027.

Overview

Response Deadline
Jan. 20, 2025, 3:00 p.m. EST Past Due
Posted
Jan. 6, 2025, 2:05 p.m. EST
Set Aside
None
Place of Performance
Bethesda, MD United States
Source
SAM

Current SBA Size Standard
1000 Employees
Pricing
Likely Fixed Price
Est. Level of Competition
Low
Odds of Award
53%
On 1/6/25 National Institute on Drug Abuse issued Sources Sought 75N95025Q00118 for SOURCES SOUGHT: Mass Spectrometry Reagents due 1/20/25. The opportunity was issued full & open with NAICS 334516 and PSC 6640.
Primary Contact
Name
Rashiid Cummins   Profile
Phone
None

Documents

Posted documents for Sources Sought 75N95025Q00118

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Additional Details

Source Agency Hierarchy
HEALTH AND HUMAN SERVICES, DEPARTMENT OF > NATIONAL INSTITUTES OF HEALTH > NATIONAL INSTITUTES OF HEALTH NIDA
FPDS Organization Code
7529-75N950
Source Organization Code
100189048
Last Updated
Feb. 4, 2025
Last Updated By
rashiid.cummins@nih.gov
Archive Date
Feb. 4, 2025