Reimagining Protein Manufacturing (RPM)

Background
The Reimagining Protein Manufacturing (RPM) program aims to ensure timely Department of Defense (DoD) access to critical medical countermeasures (MCMs) by establishing the foundational technologies needed for fully distributed, on-demand manufacturing of protein-based MCMs and associated raw materials. This technology will allow the DoD to rapidly secure access to both therapeutic proteins and enzymes needed for nucleic acid-based MCM synthesis, and reduce reliance on complex supply chains.

Work Details
The contractor shall provide the facilities and equipment necessary to develop the effort as described in the Statement of Work. The work includes two technical areas: Production Yield and Time, and Post-Translational Modifications. Each technical area has sub-tasks with detailed descriptions, performance metrics, assessment, and deliverables/milestones. Additionally, the program management and review section outlines requirements for kick-off meeting, monthly financial reports, monthly technical reporting, quarterly technical reporting, PI meetings, and final contract review. It also includes details on government furnished equipment (GFE) / contractor acquired property (CAP), travel expectations, place of performance, security clearance requirements.

Period of Performance
Base Period (Phase I): 26 months; Option 1 Period (Phase II): 24 months

Place of Performance
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