Medicinal Chemistry Consultant Support Services   2

Title: Medicinal Chemistry Consultant Support Services

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested at this time and an additional written solicitation will NOT be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13 Simplified Acquisition Procedures and FAR Part 12 Acquisition of Commercial Items.

(ii) The solicitation number is NIHDA201800016 and the solicitation is issued as a request for quotation (RFQ).

This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5- Simplified Procedures for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005 96, dated November 6, 2017. The resultant contract will include all applicable clauses in effect through this date.

(iv) The intended procurement is classified under NAICS code 541690 Other Scientific and Technical Consulting Services with a Size Standard of $15 Million.

(v) The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people's health and save lives.

The NIH Blueprint for Neuroscience Research, a consortium of 8 NIH Institutes and Centers that support neuroscience research, established the Blueprint Neurotherapeutics Network (BPN) as a pipeline between the typical endpoint of NIH funded research and the beginning of industry drug development. The BPN provides neuroscience researchers with funding and access to a full range of industry style drug development services and expertise. The program is intended for projects requiring medicinal chemistry optimization and contract research organization (CRO) support through Phase I clinical testing. Each project is directed by a Lead Development Team (LDT) composed of the principal investigator (PI), industry consultants hired by NIH, and NIH staff. This team maps out a research strategy, including milestones, and oversees implementation by CROs. Bioactivity and efficacy studies are funded through an award to the PI; other research services are provided without cost to the PI through NIH contracts.

(vi) Purpose and Objectives: The purpose of this requirement is to procure up to three (3) consultants to provide technical recommendations to the NIH Blueprint Neurotherapeutics Network drug discovery and development program in the area of Medicinal Chemistry.

(vii) Period of Performance: The required period of performance is a one year base period from February 28, 2018 through February 27, 2019 and four (4) subsequent one year option periods.

Place of Performance: The primary place of performance shall be Contractor site. Conference calls and email shall be the primary mode of communication; however, the Contractor may be required to work at Government facilities or facilities of selected principal investigators on an as needed basis.

(xiv) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.

(xv) Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price proposal must include the labor categories, an estimate of the number of hours required for each labor category, fully loaded fixed hourly rate or each labor category, breakdown and rationale for other direct costs or materials, and the total amount.

(xvi) In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov."

All responses must be received by the closing date of this announcement and must reference solicitation number NIHDA201800016 . Responses shall be submitted electronically to via e-mail to Annette Carter, Contracting Officer, at cartera@mail.nih.gov.

Fax responses will not be accepted.

The name and telephone number of the individual to contact for information regarding the solicitation. Annette Carter (301) 496-5916.