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Lipid Nanoparticle Generator System

ID: 75N98026Q00718 • Type: Solicitation • Match:  90%
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Description

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.
(ii) The solicitation number is 75N98026Q00717. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.
This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Services, and is not expected to exceed the simplified acquisition threshold (if applicable).
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a (Firm-Fixed-Price) to the responsible offeror whose proposal represents the best value to the Government.
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular effective May 29, 2026
(iv) The associated NAICS code is 811210 Electronic and Precision Equipment Repair and Maintenance and the small business size standard is $34 Millions.
This requirement is unrestricted.
Background
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, is seeking to award a Firm-Fixed-Price contract for the acquisition of a Lipid Nanoparticle Generator System. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or services. The goal is to procure a system that meets specific requirements for nanoparticle synthesis, which is essential for various biomedical applications.

Work Details
The contract involves the delivery of one (1) Lipid Nanoparticle Generator System, including required accessories, software, training, and warranty. The system must meet the following salient characteristics:
- Utilize microfluidic technology (or equivalent) for controlled and reproducible nanoparticle synthesis.
- Throughput capability: approximately 0.1 to 15 mL per sample, processing 1 to 4 samples per run.
- Adjustable flow parameters: total flow rate of approximately 3–4 mL/min and flow rate ratio of approximately 3:1 or equivalent tunability.
- Capability to produce nanoparticles with size range: ~40–200 nm and Polydispersity Index (PDI): ~0.05–0.2.
- Encapsulation efficiency of approximately 85–95% (or equivalent performance).
- Ability to encapsulate multiple payload types including DNA, mRNA, siRNA, proteins, and small molecules.
- Integrated control interface (e.g., touchscreen or software-based system) for parameter adjustment and automation.
- Compact design suitable for laboratory environments.
- Essential components included: controller, microfluidic chips, reservoirs, tubing, connectors.
- Warranty and on-site or virtual training included.

Period of Performance
08/03/2026 to 11/30/2026

Place of Performance
9808 Medical Center Drive, Building E, Room 205, Rockville, MD 20850

Bidder Requirements
Bidders must provide products that meet or exceed the specified salient characteristics. If a foreign-manufactured product is proposed, applicable regulatory requirements such as Buy American Act considerations will be addressed during the acquisition process.

Overview

Agency
NIH Office of Logistics and Acquisition Operations (OLAO) [HHS - NIH]
Response Deadline
July 22, 2026, 12:00 p.m. EDT Due in 22 Days
Posted
June 30, 2026, 8:49 a.m. EDT
Set Aside
None
NAICS
334516 - Analytical Laboratory Instrument Manufacturing
PSC
6640 - Laboratory Equipment And Supplies
Place of Performance
6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511 USA
Source
Open
Current SBA Size Standard
1000 Employees
Pricing
Fixed Price
Evaluation Criteria
Best Value
Est. Level of Competition
Average
Est. Value Range
Experimental
$50,000 - $250,000 (AI estimate)
On 6/30/26 NIH Office of Logistics and Acquisition Operations issued Solicitation 75N98026Q00718 for Lipid Nanoparticle Generator System due 7/22/26. The opportunity was issued full & open with NAICS 334516 and PSC 6640.
Primary Contact
Name
JOHNSTON, JADDUA C   Profile
Email
jaddua.johnston@nih.gov
Phone
+1 000 000 0000

Documents

Posted documents for Solicitation 75N98026Q00718

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Additional Details

Source Agency Hierarchy
HEALTH AND HUMAN SERVICES, DEPARTMENT OF > NATIONAL INSTITUTES OF HEALTH > NATIONAL INSTITUTES OF HEALTH OLAO
FPDS Organization Code
7529-75N980
Source Organization Code
100189057
Last Updated
June 30, 2026
Last Updated By
jaddua.johnston@nih.gov
Archive Date
Aug. 6, 2026