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Final Innovative Solutions Opening (ISO) ARPA-H Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID)   4

ID: ARPA-H-SOL-25-119 • Type: Solicitation

Description

Posted: March 20, 2025, 1:24 p.m. EDT

20 MAR: Note: It is permissible to join as many proposals as you would like within each RAPID program TA or across TAs. While there is statutory language that may suggest ARPA-H is limited in the number of awards it may make to one entity, there are circumstances in which ARPA-H may make more than three awards to a particular person or organization. ARPA-H encourages organizations to submit their research ideas notwithstanding this perceived limitation.This guidance supersedes the limitation noted in an earlier version of the FAQs published on the RAPID program webpage and in the Proposers' Day video. Both resources have been updated accordingly.

14 MAR: The deadline for proposals to the RAPID program (ARPA-H-SOL-25-119) is extended to April 24, 2025 05:00 pm EDT. Feedback on Solution Summaries is expected to be sent out the week of March 17-21, 2025.

Amendment 1 changes:

-The full proposal due date was extended to April 24, 2025

-All times were updated from EST to EDT

Visit the RAPID Program Page for additional materials and program updates.

21 FEB: The RAPID Patients' Day (ARPA-H-SN-25-127) event is now CANCELLED. The RAPID team will post a video and other information when possible. Questions sent to RAPID@arpa-h.gov will be answered as soon as the RAPID team is able to respond.

23 JAN: Due to circumstances outside of ARPA-H's control, the RAPID Proposers' Day event is now CANCELLED. Questions sent to RAPID@arpa-h.gov ARE UNABLE TO BE ANSWERED AT THIS TIME.

22 JAN: RAPID proposers intending to participate in the RAPID Proposers' Day are encouraged to review ARPA-H Special Notice ARPA-H-SN-25-124. Due to circumstances outside of ARPA-H's control, the RAPID Proposers' Day event will now occur only virtually. Verified/accepted participants are encouraged to verify they have received the Zoom link/invitation. Questions sent to RAPID@arpa-h.gov will be addressed as quickly as possible.

The is the final ISO for the RAPID program. RAPID aims to end or significantly reduce the prolonged diagnostic odysseys affecting millions of rare disease patients worldwide. RAPID seeks to develop novel diagnostic support tools for population-scale rare disease detection, systematically identifying and diagnosing rare disease patients more efficiently and accurately.

Posted: March 14, 2025, 9:07 a.m. EDT
Posted: Feb. 21, 2025, 11:22 a.m. EST
Posted: Jan. 23, 2025, 10:35 a.m. EST
Posted: Jan. 22, 2025, 2:21 p.m. EST
Posted: Jan. 18, 2025, 6:45 p.m. EST
Background
The Advanced Research Projects Agency for Health (ARPA-H) is issuing this solicitation as part of the RAPID program, which aims to end or significantly reduce the prolonged diagnostic odysseys affecting millions of rare disease patients worldwide.

The goal of RAPID is to develop novel diagnostic support tools for population-scale rare disease detection, systematically identifying and diagnosing rare disease patients more efficiently and accurately.

Work Details
The Statement of Work (SOW) outlines a detailed breakdown of tasks and subtasks that must be completed under the contract. Each task/subtask will include a clear and concise goal, detailed activities description, key actions and anticipated obstacles, identification of the primary organization responsible for execution, completion criteria, associated measurable milestones, deliverables such as data, reports, software, demonstrations, etc., format and delivery method, metrics for evaluating success or performance, and rationale for selecting specific metrics.

Tasks are numbered with milestones clearly defined.

Period of Performance
The contract will be performed over a specified period starting from January 10, 2025.

Overview

Response Deadline
April 24, 2025, 5:00 p.m. EDT (original: April 11, 2025, 5:00 p.m. EDT) Past Due
Posted
Jan. 18, 2025, 6:45 p.m. EST (updated: March 20, 2025, 1:24 p.m. EDT)
Set Aside
None
Place of Performance
United States
Source
SAM

Current SBA Size Standard
1000 Employees
Pricing
Likely Fixed Price
Est. Level of Competition
Average
On 1/18/25 National Institutes of Health issued Solicitation ARPA-H-SOL-25-119 for Final Innovative Solutions Opening (ISO) ARPA-H Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID) due 4/24/25. The opportunity was issued full & open with NAICS 541715 and PSC AN13.
Primary Contact
Name
RAPID Email Box   Profile
Phone
None

Documents

Posted documents for Solicitation ARPA-H-SOL-25-119

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Additional Details

Source Agency Hierarchy
HEALTH AND HUMAN SERVICES, DEPARTMENT OF > NATIONAL INSTITUTES OF HEALTH > NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
FPDS Organization Code
7529-75N992
Source Organization Code
500183629
Last Updated
March 20, 2025
Last Updated By
caitlin.burns@arpa-h.gov
Archive Date
May 9, 2025