Molecular Operating Environment (MOE) License Renewals

Background
The U.S. Environmental Protection Agency (EPA), specifically the Office of Acquisition Solutions (OAS) and the Information Technology Acquisition Division (ITAD) located in Research Triangle Park, North Carolina, is issuing this contract for the renewal of Molecular Operating Environment (MOE) licenses.

The Office of Research and Development (ORD) serves as the scientific research arm of the EPA, conducting research that informs agency decisions and supports the needs of stakeholders, including state, tribal, and community partners. ORD's work is organized into six research programs addressing pressing environmental health needs. The Center for Computational Toxicology and Exposure (CCTE) within ORD focuses on high-throughput screening data generation and chemical structure information dissemination to support toxicity prediction models.

Work Details
The contract involves acquiring licenses for the Molecular Operating Environment (MOE), a comprehensive bioinformatics, cheminformatics, molecular modeling, and computational chemistry suite. MOE includes a variety of modeling methodologies that are unique in their capabilities. Key features include:
- Advanced Scripting Language (SVL) for developing custom modeling techniques.
- A repository of community-generated SVL scripts accessible to users.
- Floating licenses allowing multiple scientists to use the software across various systems.

MOE is recognized as the only commercially available software package that provides all necessary modeling capabilities for generating multiple variant model types from a single dataset, facilitating cohesive project management and scientific documentation.

Period of Performance
12/16/2024 – 12/15/2025

Place of Performance
Research Triangle Park, North Carolina