2022 NIAID Omnibus Broad Agency Announcement   6

AMENDMENT FOUR (4) - HHS-NIH-NIAID-BAA2022-1
The purpose of Amendment Three is to provide the NIAID's response to questions received regarding the solicitation. The responses are offered for information only and do not modify or become part of this solicitation. Additional amendments may be provided as needed to address further questions and their related responses.

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AMENDMENT THREE (3) - HHS-NIH-NIAID-BAA2022-1
The purpose of Amendment Three is to:

1. Update the Date Offers Due in Beta Sam to April 18, 2022, at 3:00pm EST for Research Areas 001, 002, and 004. Please note that the Date Offers Due for Research Area 003 remains unchanged as March 18, 2022, at 3:00pm EST;
2. Provide a cut-off date of April 1, 2022 for questions from potential offerors under Research Areas 001, 002, and 004; and
3. Provide the NIAID's response to questions received regarding the solicitation. The responses are offered for information only and do not modify or become part of this solicitation. Additional amendments may be provided as needed to address further questions and their related responses.

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AMENDMENT TWO (2) - HHS-NIH-NIAID-BAA2022-1
The purpose of Amendment Two is to:
1. Provide a Sample Task Linked Budget as specified in Amendment 1, GENERAL QUESTIONS APPLICABLE TO ALL RESEARCH AREAS, Question 12.
2. Correct the cut-off date for questions from potential offerors under Research Area 003 to March 1, 2022.
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AMENDMENT ONE (1) - HHS-NIH-NIAID-BAA2022-1
The purpose of Amendment One is to:
1. Provide the NIAID's response to questions received regarding the solicitation. The responses are offered for information only and do not modify or become part of this solicitation. Additional amendments may be provided as needed to address further questions and their related responses.
2. Provide a cut-off date of March 1, 2022 for questions from potential offerors under Research Area 003.
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NIAID 2022 OMNIBUS BROAD AGENCY ANNOUNCEMENT (BAA) NO. HHS-NIH-NIAID-BAA2022-1 contains four (4) distinct Research Areas, each with a specified closing date and time. The proposal due date of March 18, 2022, specified in this solicitation posting, is the due date for Research Area 003 only. An Amendment will be issued at a later date to update the proposal due date for responses to Research Areas 001, 002, 004. The proposal due dates for each Research Area are identified below:

Research Area 001 - Development of Vaccine Candidates for Biodefense, Antimicrobial Resistant (AMR) Infections and Emerging Infectious Diseases

Proposals Due Date and Time - 3:00PM Eastern Time on April 18, 2022

Research Area 002 - Development of Therapeutic Candidates for Biodefense, Antimicrobial Resistant (AMR) Infections and Emerging Infectious Diseases

Proposals Due Date and Time - 3:00PM Eastern Time on April 18, 2022

Research Area 003 - The Antiviral Program for Pandemics (APP): Development of Antivirals for Specific RNA Viral Families of Pandemic Potential

Proposals Due Date and Time - 3:00PM Eastern Time on March 18, 2022

Research Area 004 - Development of In Vitro Diagnostics for Biodefense, Antimicrobial Resistant Infections (AMR), and Emerging Infectious Diseases

Proposals Due Date and Time - 3:00PM Eastern Time on April 18, 2022