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UEI: GZT3NSK4GD15 • CAGE: 9FF48

Overview

Awardee Type
Parent
Federal Capability Statement
BreakSight offers one of the first commercial platforms that specifically examines how precision oncology treatments damage cells' DNA at the sequence level. By capturing and analyzing site-specific patterns of DNA breakage, we help researchers and drug developers better understand the biological mechanisms driving therapeutic response and discover new DNA biomarkers genomic clues that can predict whether a drug will be effective for specific patients. Nearly all current biomarkers exist as mutations in expressed genes, which constitute only 2% of the genome, limiting biomarker discovery to a narrow range within the cells' DNA. Through break signature analysis across both the coding and non-coding regions, our platform expands DNA biomarker discovery from the current 2% of the genome to the remaining 98%. As we look to innovate in the clinical space, we aim to add layers of biological insights to existing genetic data to increase diagnostic power and improve treatment decisions.
Keywords
DNA damage, genomic instability, biomarker discovery, DNA break mapping, Synthetic Lethality, Replication Stress, DDR
Website
https://www.breaksightdna.com
Headquarters
Allentown, PA
United States
Federal recipient BREAKSIGHT, INC. (UEI GZT3NSK4GD15, CAGE 9FF48) is headquartered in Allentown PA. Its primary registered NAICS is 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). The corporation was founded in March 2018 and federally registered in January 2023.

Federal Registration and Certifications

Legal Name
BREAKSIGHT, INC.
UEI
GZT3NSK4GD15
CAGE Code
9FF48
Primary NAICS
541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
SBA Certifications
None
Self Certifications
For Profit Organization
Entity Structure
Corporate Entity (Not Tax Exempt)

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