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Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

ID: PAR-26-074 • Type: Forecasted
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Description

This Notice of Funding Opportunity (NOFO) aims to build new research capacity by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.

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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Grant
Grant Program (CFDA)
93.351 - Research Infrastructure Programs
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 11/19/25 the National Institutes of Health forecasted grant opportunity PAR-26-074 for Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed) with funding of $5.0 million. The grant will be issued under grant program 93.351 Research Infrastructure Programs. It is expected that 15 total grants will be made worth between $50,000 and $400,000.

Timing

Forecast Posted Date
Nov. 19, 2025, 12:00 a.m. EST
Est. Application Posting Date
Feb. 28, 2026, 12:00 a.m. EST
Est. Synopsis Response Date
July 1, 2026, 12:00 a.m. EDT Forecasted
Last Updated
Nov. 19, 2025, 8:57 a.m. EST
Version
1

Eligibility

Eligible Applicants
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
Private institutions of higher education

Award Sizing

Ceiling
$400,000
Floor
$50,000
Estimated Program Funding
$5,000,000
Estimated Number of Grants
15

Contacts

Contact
Xiang-Ning Li, MD, PhD
Contact Email
xiang-ning.li@nih.gov   Profile

Documents

Posted documents for PAR-26-074

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