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Drug-Free Communities (DFC) Support Program - (Year 6 - FY25 Cohort)

ID: CDC-RFA-CE-26-0208 • Type: Posted
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Description

Posted: Dec. 22, 2025, 12:00 a.m. EST
The Drug-Free Communities (DFC) Support Program was created by the Drug-Free Communities Act of 1997 (Public Law 105-20). The Executive Office of the President, Office of National Drug Control Policy (ONDCP), and the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), National Center for Injury Prevention and Control (NCIPC) are accepting applications for Fiscal Year (FY) 2026 Drug-Free Communities (DFC) Support Program Grants. The purpose of the DFC Support Program is to establish and strengthen collaborations to support the efforts of community coalitions working to prevent and reduce substance use among youth. By statute, the DFC Support Program has two goals: 1) Establish and strengthen the collaboration among communities, public and private non-profit agencies, as well as federal, state, local, and tribal governments to support the efforts of community coalitions working to prevent and reduce substance use among youth (individuals 18 years of age and younger). 2) Reduce substance use among youth and, over time, reduce substance use among adults by addressing the factors in a community that increases the risk of substance use and promoting the factors that minimize the risk of substance use. This funding opportunity will fund applicants who have concluded the first (Year 1 5) funding cycle or have experienced a lapse in funding.
Posted: Dec. 8, 2025, 12:00 a.m. EST
Posted: Dec. 8, 2025, 12:00 a.m. EST
Background
The Drug-Free Communities (DFC) Support Program was established by the Drug-Free Communities Act of 1997. The program is administered by the Executive Office of the President, Office of National Drug Control Policy (ONDCP), and managed by the CDC's National Center for Injury Prevention and Control (NCIPC).

The DFC Support Program aims to strengthen community coalitions to prevent and reduce substance use among youth, with a focus on collaboration among various stakeholders including public and private organizations, as well as federal, state, local, and tribal governments.

Grant Details
The DFC Support Program will fund community coalitions that have either completed the first five-year funding cycle or have experienced a lapse in funding. The program's goals include establishing collaborations to address youth substance use and reducing substance use among both youth and adults over time.

Funded projects will implement evidence-based strategies to address risk factors in communities that contribute to substance use. Applicants must demonstrate their capacity to manage the grant effectively and provide a detailed work plan outlining specific objectives, strategies, and activities aligned with DFC goals.

Eligibility Requirements
Eligible applicants include community-based coalitions that have received a DFC grant in previous years (Year 1-5) and are based in the United States or U.S. territories. Coalitions must meet specific statutory requirements including representation from 12 required sectors, having a mission focused on preventing youth substance use, addressing at least two substances, securing a 100% match from non-federal sources, and not exceeding 10 years of DFC funding.

Period of Performance
The period of performance for this grant is five years, divided into twelve-month budget periods. The expected start date for funded projects is July 1, 2026.

Grant Value
The total expected funding for the program over its performance period is $31,250,000. Each applicant may receive up to $125,000 per year for five years.

Place of Performance
The grant activities are expected to be carried out within the United States or U.S. territories.

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
True
Source
On 12/22/25 Injury Center posted grant opportunity CDC-RFA-CE-26-0208 for Drug-Free Communities (DFC) Support Program - (Year 6 - FY25 Cohort) with funding of $50.0 million. The grant will be issued under grant program 93.276 Drug-Free Communities Support Program Grants. It is expected that 80 total grants will be made.

Timing

Posted Date
Dec. 22, 2025, 12:00 a.m. EST
Closing Date
Feb. 12, 2026, 12:00 a.m. EST Due in 25 Days
Closing Date Explanation
Electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date.
Last Updated
Dec. 22, 2025, 5:08 p.m. EST
Version
1
Archive Date
March 14, 2026

Eligibility

Eligible Applicants
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Others (see text field entitled "Additional Information on Eligibility" for clarification)
County governments
Native American tribal governments (Federally recognized)
Private institutions of higher education
Public and State controlled institutions of higher education
City or township governments
Independent school districts
Additional Info
Eligible applicants are community-based coalitions addressing youth substance use that have previously received a DFC grant (Year 1–5), have experienced a lapse in funding, or have concluded the first five-year funding cycle and are applying for a second five-year funding cycle. Applicants must be a nonprofit (as defined by the IRS as a 501(c) organization); or an entity that the Administrator determines to be appropriate; or part of, or is associated with an established legally recognized domestic, public or private nonprofit organization. For example, state and local governments, federally recognized tribes, state-recognized tribes, urban Indian organizations (as defined in Pub. L. No. 94-437), public or private universities and colleges, professional associations, voluntary organizations, self-help groups, consumer and provider services-oriented constituency groups, community- and faith-based organizations, and tribal organizations. (Pub. L. No. 114-198 Sec 103). For the purposes of this NOFO and the DFC Support Program, a coalition is defined as a community-based formal arrangement for cooperation and collaboration among groups or sectors of a community in which each group retains its identity, but all agree to work together toward a common goal of building a safe, healthy, and drug-free community. In furtherance of the Trump Administration's Statement of Drug Policy Priorities, the DFC Support Program is committed to protecting American youth from the dangers of drug use. DFC Support Program applicants are expected to support applicable Executive Orders, including but not limited to: Executive Order 14168: Defending Women From Gender Ideology Extremism and Restoring Biological Truth to the Federal Government, Executive Order 14159: Protecting the American People from Invasion, Executive Order 14173: Ending Illegal Discrimination and Restoring Merit-Based Opportunity, Executive Order 13768: Enhancing Public Safety in the Interior of the United States, Executive Order 14182: Enforcing the Hyde Amendment.

Award Sizing

Ceiling
$125,000
Floor
Not Listed
Estimated Program Funding
$50,000,000
Estimated Number of Grants
80

Contacts

Contact
Centers for Disease Control - NCIPC
Contact Email
Contact Phone
(770) 488-2756

Documents

Posted documents for CDC-RFA-CE-26-0208

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