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75N91023C00042

Definitive Contract

Overview

Government Description
ARPA-H SBIR PHASE II TOPIC ARPA-H 04 INTRA-OPERATIVE CONTRAST AGENTS
Awarding / Funding Agency
Place of Performance
Portland, OR 97239 United States
Pricing
Fixed Price
Set Aside
Small Business Set Aside - Total (SBA)
Extent Competed
Full And Open Competition After Exclusion Of Sources
Analysis Notes
Amendment Since initial award the Potential Award value has increased 3% from $4,098,757 to $4,218,974.
Trace Biosciences was awarded Definitive Contract 75N91023C00042 (75N910-23-C-00042) for Arpa-H Sbir Phase Ii Topic Arpa-H 04 Intra-Operative Contrast Agents worth up to $4,218,974 by the National Institutes of Health in September 2023. The contract has a duration of 4 years and was awarded through solicitation A Solicitation of the Advanced Research Project Agency for Health (ARPA-H) for Small Business Innovative Research (SBIR) Contract Proposals- SOLICITATION AND ALL AMENDMENTS (1-4) with a Small Business Total set aside with NAICS 541715 and PSC AN13 via direct negotiation acquisition procedures with 2 bids received.

SBIR Details

Research Type
Small Business Innovation Research Program (SBIR) Phase I
Title
ARPA-H SBIR PHASE II TOPIC ARPA-H 04 INTRA-OPERATIVE CONTRAST AGENTS
Abstract
This project plans to synthesize and characterize novel nerve-specific fluorescence guided surgery (FGS) contrast agents to select a bright, water-soluble lead compound for clinical translation with optimal nerve visualization, functional assessment performance, and clinically relevant pharmacology and toxicology (pharm/tox) profiles for follow-on Investigational New Drug-enabling studies and first-in-human trials.
Research Objective
The goal of phase I is to establish the technical merit, feasibility, and commercial potential of proposed R&D efforts and determine the quality of performance of the small business awardee organization.
Topic Code
AH04
Agency Tracking Number
75N91023C00042
Solicitation Number
75N91023R00041
Contact
Connor Barth

Status
(Open)

Last Modified 7/16/25
Period of Performance
9/15/23
Start Date
9/14/27
Current End Date
9/14/27
Potential End Date
54.0% Complete

Obligations
$4.2M
Total Obligated
$4.2M
Current Award
$4.2M
Potential Award
100% Funded

Award Hierarchy

Definitive Contract

75N91023C00042

Subcontracts

0

Activity Timeline

Interactive chart of timeline of amendments to 75N91023C00042

Labor Services Billing

Annual labor billing rates and FTE reported for 75N91023C00042

Opportunity Lifecycle

Procurement history for 75N91023C00042

Transaction History

Modifications to 75N91023C00042

People

Suggested agency contacts for 75N91023C00042

Competition

Number of Bidders
2
Solicitation Procedures
Negotiated Proposal/Quote
Evaluated Preference
None
Performance Based Acquisition
Yes
Commercial Item Acquisition
Commercial Item Procedures Not Used
Simplified Procedures for Commercial Items
No

Other Categorizations

Subcontracting Plan
Plan Not Required
Cost Accounting Standards
Exempt
Business Size Determination
Small Business
Awardee UEI
YGDTEJXJC9G8
Awardee CAGE
9HEB7
Agency Detail
Awarding Office
75N992 ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Funding Office
75N992
Created By
hhslharris3
Last Modified By
hhsssnyder
Approved By
hhsssnyder

Legislative

Legislative Mandates
None Applicable
Performance District
OR-01
Senators
Jeff Merkley
Ron Wyden
Representative
Suzanne Bonamici

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
Advanced Research Projects Agency for Health-NIH, National Institutes of Health, Department of Health and Human Services (075-0837) Health research and training Other services from non-Federal sources (25.2) $599,180 100%
Modified: 7/16/25